科隆大学和科隆大学医院的研究人员证明，基于 mRNA 的新型 COVID-19 疫苗不仅会触发适应性免疫反应（例如产生抗体），还会诱导先天免疫细胞发生持久的表观遗传变化。这项研究由科隆大学医院传染病科主任、科隆分子医学中心 (CMMC) 首席研究员 Jan Rybniker 教授和 CMMC 首席研究员 Robert Hänsel-Hertsch 博士共同领导。研究结果发表在《分子系统生物学》杂志 ...

Not surprisingly, mRNA-stability determinants are found predominantly in the 3′ UTR where protein complexes are sheltered from traversing ribosomes, but they are also found in the 5′ UTR and ...

During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

Messenger RNA carries genetic information from DNA in the highly protected nucleus out to the rest of the cell, where structures called ribosomes can build proteins according to the DNA blueprint.

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

MRNA technology is facing growing doubts among Republicans. This is a KFF Health News story. Researchers racing to develop bird flu vaccines for humans have turned to a cutting-edge technology ...

MRNA, which stands for messenger ribonucleic acid, is a molecule that copies your DNA’s instructions and brings them to the protein-making structures in your cells, called ribosomes. The ...

By recruiting ribosomes, IRES sequences enable the initiation of translation independently of the 5' cap of the mRNA. This is a protective cap with which the host's own mRNA strands are equipped ...