而且，MSC - UBvR - OVA 增强抗原呈递的能力不依赖于抗原加工和加载相关基因的表达变化，也不依赖于 MHC I 类分子细胞表面表达的增加。此外，该研究还揭示了 ROS 在 UBvR 降解标签介导的抗原降解和呈递过程中的重要作用，以及 MSC - UBvR - OVA 疫苗在体内发挥作用 ...

Combine a garden-variety green laser, microwaves with roughly the energy of your wi-fi, and some diamond dust in drops of water, and what do you get? A precise chemical detection tool.

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黑素细胞表达的 MHC - II 分子，可以将处理后的抗原呈递给 T 淋巴细胞 ... 氧化应激是指细胞内活性氧（Reactive Oxygen Species，ROS）产生过多或抗氧化防御系统功能下降，导致氧化与抗氧化平衡失调的状态。黑素细胞在正常代谢过程中会产生一定量的 ROS，当受到 ...

在肿瘤免疫治疗与营养代谢交叉领域，维生素C（vitC）的抗癌机制长期存在争议。传统研究聚焦于vitC通过产生活性氧（ROS）或作为TET酶的辅助因子发挥表观遗传调控作用，但这些机制无法完全解释高剂量vitC在临床中表现出的免疫增强效应。关键问题在于：vitC是否通过未知的直接分子机制调控免疫信号通路？

This could be achieved by an increase in classical monocytes. However, increased antigen uptake must be carefully balanced against a suppression of antigen-presenting functions to lymphocytes in order ...

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, United States; Department of Microbiology, UMass Chan Medical School, United States; ...

Interleukin-27 (IL-27) is a member of the IL-12 family. The gene encoding IL-27 is located at chromosome 16p11. IL-27 is considered as a heterodimeric cytokine, which consists of Epstein–Barr virus ...

Mar. 18, 2025 — Although fungi of the genus Piloderma are common, scientists have now discovered five previously unknown species. One of these is one of the most widely distributed species in ...

This important study reveals that disrupting fatty acid metabolism in macrophages significantly restricts the growth of Mycobacterium tuberculosis, showing that impaired lipid processing triggers ...