在氯化血红素刺激的 SH-SY5Y 细胞中，观察到 ROS 和 MDA 含量增加、SOD 活性降低、铁水平升高，以及 GPX4、FTH1、SLC7A11 和 SOX2 下调，而 EUP 逆转了这些变化。此外，沉默 SOX2 消除了 EUP 对氯化血红素刺激的 SH-SY5Y 细胞氧化应激和铁死亡的影响。总体而言，EUP 通过抑制 ...

This study presents a valuable finding on how the interplay between transcription factors SOX2 and OCT4 establishes the pluripotency network in early mouse embryos. The evidence supporting the claims ...

Combine a garden-variety green laser, microwaves with roughly the energy of your wi-fi, and some diamond dust in drops of water, and what do you get? A precise chemical detection tool.

Mar. 12, 2025 — A critically endangered new species of killifish sampled from an ancient forest in Kenya in 2017 and 2018 has now been described. Nothobranchius sylvaticus, from the Latin ...

The study of hPSC-derived retinal organoids (ROs) increased in popularity over the last decade. ROs recapitulate the complex architecture of the tissue found in the human retina (Li et al., 2021).

In a study published in Microbiological Research, scientists from Surrey investigated how different RNS and ROS ratios affect harmful bacteria, including Staphylococcus aureus, Enterococcus ...

Liver disease is a significant global health issue, responsible for millions of deaths annually. Aging, characterized by the gradual decline in cellular and physiological functions, impairs tissue ...