为解决鼻咽癌早期诊断难题，研究人员分析 S100A9 和 CCL5 水平，构建模型，发现其有诊断价值及临床实用性。 《多参数诊断模型：基于 S100A9、CCL5 及血液标志物精准诊断鼻咽癌》 在人体的 “健康版图” 中，鼻咽癌就像一颗潜藏的 “暗雷”，尤其在中国南方和 ...

reuma.umcn.nl Objective: To study the active involvement of Myeloid-related proteins S100A8 and S100A9 in joint inflammation and cartilage destruction during antigen-induced arthritis (AIA). Methods: ...

Background Synovitis-associated pain is an important aspect of arthritis pathology. Several inflammatory mediators released by the synovium have been implicated in the regulation of pain, including ...

Ten small-molecule drugs associated with COPD and NASH were identified through cMAP analysis, including ansoprazole and atovaquone. In addition, we further identified the hub genes S100A9 and MYH2 for ...

Auto-inhibitory regulation of S100A8/S100A9-alarmin activity locally restricts sterile inflammation. J. Clin. Invest. 128; 1852-1866. Ulas T, Pirr S, Fehlhaber B, Bickes M, Loof TG, Vogl T, Mellinger ...

RT-PCR confirmed that NaB treatment inhibited the expression of inflammation related genes such as S100a9 and Ccl4 found upregulated in the brain of cDKO mice. Surprisingly, the level of brain histone ...

Metabolic disorders occur when the body's usual metabolic processes are disrupted. These diseases can be congenital or acquired, for example, diabetes and phenylketonuria. This Review discusses ...

Objectives Tendinopathy is a frequent clinical problem and represents an extraordinary health economic and socioeconomic ...

Dr. Michael Schäfers, European Institute for Molecular Imaging C03 Targeting S100A8/S100A9 induced MDSCs in inflammatory disorders Contact person: Dr. Sven Hermann, European Institute for Molecular ...

Sepsis-induced skeletal muscle atrophy is linked to increased mortality in septic patients; in this study, the authors identify the S100a8/a9-RAGE pathway as a key driver of mitochondrial ...

Ischemic cardiomyopathy (ICM) is the end stage of ischemic heart disease, in which ventricular remodeling contributes to a fatal ventricular arrhythmia, worsens heart function and unfavorable outcomes ...