该研究发现鼻黏膜 sIgA 比血清抗体具有更强且更广谱的中和活性，凸显了上呼吸道黏膜 sIgA 在预防新冠病毒感染方面的重要作用，也为设计能有效诱导上呼吸道产生sIgA的鼻喷疫苗提供了依据。

该论文系统论述了中亚古今人群的基因组研究进展，并提出了未来构建中亚人群大规模特异性基因组资源库的方案。人类古今基因组研究不仅有助于阐明人群的起源、迁徙、演化及混合历史，还在系统解析人群疾病与健康的遗传调控机制、揭示复杂性状遗传学基础的时空演化轨迹并推 ...

It's been five years since COVID-19 was declared a global pandemic. As SARS-CoV-2 shifts to endemic status, questions about ...

As scientists, we often think we understand a virus—its structure, its tricks, the way it moves through the body. But every ...

The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2. Although vaccines ...

Viruses like SARS-CoV-2 use sugar molecules to hide from the immune system, but scientists at Scripps Research have designed ...

Small-molecule inhibitors targeting viral proteins could serve as an effective alternative for controlling the spread of COVID-19 at both individual and community levels. In this vein, a recent study ...

Analysis - More than five years since COVID was declared a pandemic, we're still facing the regular emergence of new variants ...

Early animal studies show that a single vaccine could protect the recipient from different variants of the coronaviruses that cause COVID-19, the flu and the common cold. In addition to creating ...