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为解决结直肠癌(CRC)转移机制不明及缺乏有效治疗靶点的问题,研究人员开展了 NR3C2-SIRT1 信号轴在 CRC 转移机制中作用的研究。结果发现该信号轴促进自噬、抑制上皮 - 间质转化(EMT),抑制 CRC 肺转移,为 CRC 治疗提供潜在靶点。
(MENAFN- Quintile Reports) The Global Western Blotting Market was estimated at USD 2.2 billion in 2025 and is projected to reach USD 4.38 billion by 2034 , reflecting a robust CAGR of 6.61% over ...
How alterations in cell metabolism translate into specific developmental gene programs remains a major question. This study ...
Figure 7. NMN reverses the decline of mitochondrial-related proteins tissue of aging mice. Panels (A–C) represent the protein expression levels of Sirt1, PGC1α, and phosphorylated AMPK (P-AMPK) in the ...
Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, Laboratory of Neuro-system and Multimorbidity, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China ...
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