Long-lived plasma cells, which produce autoantibodies in diseases such as systemic lupus erythematosus (SLE), are an as yet unexplored therapeutic target in such antibody-mediated disorders.

系统性红斑狼疮（SLE）是一种典型的“自作自受”的免疫系统错误，它让免疫系统误以为健康细胞是敌人，开始大举进攻。这种慢性疾病，常常给患者带来全身性的疼痛和不适，尤其是在皮肤、关节、肾脏等部位表现最为明显。

SLE affects virtually every organ/system in the body. The key to its successful treatment is the prevention of damage. It is also important to recognize that at least one-third of SLE patients ...

In a new study, researchers explored experiences, perceptions, and health effects of a newly developed healthy lifestyle ...

Researchers identified 4 prepregnancy conditions that were associated with better pregnancy outcomes among patients with SLE.

These concurrent developments have lead to the concept that inflammatory mediators operative in RA and SLE might be causal in the accelerated atherosclerosis observed, a concept supported by ...

For patients with SLE manifestations in the CNS or peripheral nervous system, lungs, heart, GI tract or the eyes, the first line of treatment should be (much) higher dosages of glucocorticoids.

The treatment for SLE varies depending on the symptoms but often includes anti-inflammatory drugs like ibuprofen. In the UK, ...

Having established success in cancer, biopharma is now looking to leverage CAR T therapies against a new target, autoimmune ...

In a new study, researchers explored experiences, perceptions, and health effects of a newly developed healthy lifestyle intervention for people with systemic lupus erythematosus (SLE). This study ...

LA JOLLA, CA, March 31, 2025 (GLOBE NEWSWIRE) -- GRI Bio, Inc. (NASDAQ: GRI) ("GRI Bio” or the "Company”), a biotechnology ...

Baseline factors linked to SLE flares during pregnancy included thrombocytopenia and a history of LN, while antimalarial therapy demonstrated protective effects.