宁波大学附属第一医院的研究人员勇挑重担，开展了一项意义重大的研究。他们将目光聚焦于信号转导与转录激活因子（STAT）家族，这个家族在细胞周期、免疫反应和肿瘤发展过程中发挥着至关重要的作用，可其在结直肠癌中的功能和表达情况此前却并不明确。研究人员经过深入探索，发现 STAT3 和 STAT5B ...

All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three broad categories, although there are exceptions. For example, nimesulide is a weak competitive ...

Meloxicam is an enolcarboxamide with preferential COX-2 inhibitory activity. In vitro studies with human tissues have confirmed the high affinity of meloxicam for COX-2, whereas COX-1 was ...

The Last of Us Part 2 Remastered will release on April 3, 2025, for players on PC. As revealed during The Game Awards 2024, the Ellie-focused sequel heads to PC with a few upgrades beyond the ...

Who's ready to play Sara's new game? Get all the details here.

Nintendo Switch 2 is finally confirmed. After literal years of unverified rumors, dubious leaks and copious amounts of online speculation, Nintendo has lifted the lid on its next-generation ...

Dodge & Cox’s January 2025 personnel update suggests ... the team recently increased the portfolio's duration to 6.2 years, in line with the index's, based on the belief that both rates and ...

Dodge & Cox’s January 2025 personnel update suggests ... return far outpaced the typical moderate allocation peer’s 6.2% annualized return and the Morningstar Moderate Target Risk Index ...

Rom's joined live in the studio for lots of laughs, with comedian Ellie Taylor. Read more ...

2 Here, we show that Yap is highly expressed by SF in both human RA and mouse AIA and that conditional genetic ablation of Yap in SF ameliorates AIA. Mechanistically, Yap is Jak-dependently activated ...

The Fund’s primary objective is to provide shareholders with an opportunity for long-term growth of principal and income. A secondary objective is to seek to achieve a reasonable current income. The ...