Here, we showed that sunitinib induces a metabolic shift leading to increased serine synthesis in RCC cells. Activation of the GCN2-ATF4 stress response pathway was identified as the mechanistic link ...

A natural antibacterial molecule shows clinical promise. Its unusual binding site is on an excellent target: ...

List of useful data augmentation resources. You will find here some not common techniques, libraries, links to GitHub repos, papers, and others. This repository collects papers for "A Survey on ...

In summary, activated hemocytes increase the uptake of methionine to ramp up the transmethylation pathway. SAM is not only a substrate for methylation, but is also used for polyamine synthesis.

summarized the main features of metabolic reprogramming in tumors, addressing different aspects including increased glycolytic metabolism, lipid synthesis, alteration in amino acids production ... In ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

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Mar. 13, 2025 — When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life. A new study sheds light on changes to the fetus's ...

This study revealed a two-step mechanism of mRNA trafficking and translation, emphasizing the importance of spatial and temporal precision in linking protein synthesis to synaptic activation ...

State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, National Biomedical Imaging Center, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, College of Future ...

3 Department of Medicine, Dept. of Pathology, and Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, USA Correspondence to Dr David Tuveson, Li Ka ...