Doctors noticed that patients who had sickle cell anemia, a serious hereditary blood disease, were more likely to survive malaria, a disease which kills some 1.2 million people every year.

On this map, the distribution of sickle-cell anemia haplotypes among nations with high prevalence of the disease are shown. Five distinct beta-globin haplotypes (indicated by colors) are found in ...

The cells' sickle shape and associated fragility result in rapid RBC destruction by a patient's own body. This leads to leads to anemia, as well as congestion and fibrosis of the spleen at an ...

The quality of life of patients with sickle cell anemia is severely compromised similar to or even worse than patients with other chronic diseases such as arthritis. Patients who responded to ...

A new type of bone marrow transplant can cure sickle cell disease with only half of the donor's cell proteins matching, according to new clinical trial results published in the New England Journal of ...

Esther Nkemakolam runs her fingers through kinetic sand and sings a “Moana” song as UPMC Children’s Hospital nurse Taylor ...

The UAB Comprehensive Sickle Cell Center brings together scholars and researchers working in the forefront of basic, translational and clinical research, with the overarching goals to discover new ...

But not if you suffer from sickle cell disease, which affects nearly eight million people worldwide, most in sub-Saharan Africa. In the UK, approximately 17,500 people have sickle cell disease and ...

The underutilization of disease-modifying therapy by people with sickle cell disease is “persistent and alarming,” according to an analysis of real-world data.The findings, presented in December at ...

Children with sickle cell disease, a chronic hemolytic anemia, present with a wide variety of neurological syndromes, including ischemic and hemorrhagic stroke, transient ischemic attacks ...

Sickle cell disease is a genetic blood disorder characterised by the production of abnormal haemoglobin, which causes red blood cells to become rigid and sickle-shaped. These cells tend to clump ...

This makes it difficult for those with Sickle Cell Anemia, who are of African descent. “Many of those patients require up to 100 transfusions of blood every single year. It’s a very painful ...