In this study, we unveil a common mechanism underlying these observations for the DNA-scaffolded enzymes that acts on enzymes independent of their catalytic mechanisms. By testing a variety of ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

Previously the author has published on the discovery of the Connectase enzymes and has shown its utility in tagging proteins and detecting ... Connectase specifically can provide some benefits over ...

Enzymes catalyze nearly all of the chemical reactions that occur in biological systems. Enzymes are generally proteins but also include catalytic DNA and catalytic RNA. As effective biological ...

It enables the generation of defined and completely labeled antibody conjugates with one fusion partner on each chain. The reaction requires short incubation times with small amounts of enzyme and is ...

Molecular mechanism studies demonstrated that FMN had this effect because it could target the activation of the Nrf2 pathway, increase the activity of the phase II metabolizing enzyme glutathione ...

Department of Materials Science and Engineering, Drexel University, Philadelphia, Pennsylvania 19104, United States ...

The molecular dynamics of Trypanosoma brucei UDP-galactose 4'-epimerase: a drug target for African sleeping sickness.

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...