Numerous mechanism and structural studies reported the cooperative role of Oct4 and Sox2 during the establishment of pluripotency during reprogramming. Due to the difficulty in sample collection and ...

This study presents a valuable finding on how the interplay between transcription factors SOX2 and OCT4 establishes the pluripotency network in early mouse embryos. The evidence supporting the claims ...

Principal Investigator at University of Cambridge, Co-founder and CTO of CardiaTec Biosciences & Co-founder of KURE.ai ...

1、无菌条件下，取出1-3d 龄SD大鼠心房组织，然后用PBS将此组织块清洗2次，将组织剪成1mm3左右大小； 2、往组织块中加入4 mL酶消化液（0.1% 胰酶和0.1% I型胶原酶），混悬10s，置37℃条件下消化10min，之后用滴管吹打制成单细胞悬液，自然沉淀并收集上清，用含10% ...