TLR7 识别单链 RNA（ssRNA），激活树突状细胞，进而激活细胞毒性 T 细胞，具有抗肿瘤活性 。TLR8 的作用目前研究较少，它能识别细菌核酸，其与乳腺癌的关联还需进一步探索 。TLR9 激活可促进乳腺癌细胞增殖和侵袭，产生促炎细胞因子和生长因子，营造免疫抑制 ...

Captain John Parker’s Lexington militia company returning fire on British light infantry who had fired upon them, killing eight and wounding 10 others. Many volumes have been published telling ...

Streamlight, Inc. launched four new “Lights for a Cause” models to support two major non-profit organizations. EAGLEVILLE, PA, April 14, 2025 - Streamlight Inc., a leading provider of high ...

Sepsis is a life-threatening condition caused by a dysregulated host response to infection, remaining a major global health challenge despite clinical advances. Therapeutic challenges arise from ...

刺激 Treg 和肿瘤细胞中的 TLR8 信号，使用 cAMP 抑制剂可避免肿瘤诱导的 T 细胞衰老，TLR8 拮抗剂可降低肿瘤细胞中 cAMP 水平，抑制肿瘤来源 Tregs 的糖酵解，且不干扰效应 T 细胞代谢，有效防止 T 细胞衰老，但这些通路涉及免疫细胞功能的多个方面，抑制 STAT 或 ...

The FRCE is giving away 2,500 bags for PPE storage for safety, health, and cultural change in the fire service. The First Responder Center for Excellence (FRCE) is proud to announce the giveaway ...

Malaria, caused by infection with protozoan parasites of the genus Plasmodium, is a major global heath problem and is responsible for the deaths of over a million people annually, mainly children ...