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基于结构的数字化药物研发 :水木药业基于自有冷冻电镜集群、GPCR平台和AI技术,全球第一个成功获取了新一代肥胖靶点GPR75的高分辨冷冻电镜结构,大幅提升了小分子药物发现和优化效率,有机会成为超越斯美格鲁肽的新一代减肥小分子药物。
Structural biology is the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their ...
In January 2004, Nature Structural Biology will be renamed Nature Structural & Molecular Biology. The title change effectively represents a 'relaunch' of the journal, and it formalizes our ...
The Structural Biology and Biophysics cluster provides graduate training in this exciting and important area for biomedical research that draws upon concepts and approaches from biology, chemistry, ...
These dynamic changes are quantative and can be used as structural markers to screen novel rexinoids for similar binding characteristics. We also correlate our results with more traditional molecular ...
Our laboratory uses a combination of structural biology and biophysical techniques to discover how ion channels and membrane-embedded enzymes function at the atomic level. The proteins we study are ...
Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases.
Thesis and dissertation based Master of Science (MS) and Doctor of Philosophy (PhD) degrees are offered in Biology and Botany. Botany also offers the Master of Arts (MA) degree. Students in the ...
Modern biological sciences are enriched by the revolution in structural biology. Advances in techniques such as electron microscopy (EM), X-ray crystallography and NMR, coupled with modern biophysical ...
In our studies we use integrated computational, biochemical and structural methods including X-ray crystallography ... We are also interested in synthetic biology, where life processes are harnessed ...
It is open to all students and reserchers. The program can be found here, see the section for seminar series. Molecules club seminar, Viikki The seminar series is a campus-wide structural biology, ...