基于结构的数字化药物研发 ：水木药业基于自有冷冻电镜集群、GPCR平台和AI技术,全球第一个成功获取了新一代肥胖靶点GPR75的高分辨冷冻电镜结构,大幅提升了小分子药物发现和优化效率,有机会成为超越斯美格鲁肽的新一代减肥小分子药物。

He spent 9 years with the company helping to build one of the largest structural biology groups in industry, and became Head of Structural Biology and Bioinformatics. “However, during the late ...

Structural biology is the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their ...

The Structural Biology and Biophysics cluster provides graduate training in this exciting and important area for biomedical research that draws upon concepts and approaches from biology, chemistry, ...

These dynamic changes are quantative and can be used as structural markers to screen novel rexinoids for similar binding characteristics. We also correlate our results with more traditional molecular ...

The scientists at Boston Biomedical combined the power of several techniques including X-ray crystallography, resonance energy transfer and molecular modeling to obtain a three-dimensional, atomic ...

Thesis and dissertation based Master of Science (MS) and Doctor of Philosophy (PhD) degrees are offered in Biology and Botany. Botany also offers the Master of Arts (MA) degree. Students in the ...

Modern biological sciences are enriched by the revolution in structural biology. Advances in techniques such as electron microscopy (EM), X-ray crystallography and NMR, coupled with modern biophysical ...

We require applicants to hold, or be about to obtain, an Upper Second class Honours degree, or the equivalent qualification gained outside the UK, in a related subject area for entry to a PhD ...

Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to chromatin remodeling, a process implicated in cancer and developmental ...