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The RNA cloud formed around genes regulates their readout into RNA. Triplexes help define where in the genome a cloud forms. Proteins and other fl ...
But when U.S. National Institute of Standards and Technology researchers Christina Bergonzo and Alexander Grishaev put ...
Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The ...
Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...
However, these models often focus on deoxyribonucleic acid (DNA) or protein sequences ... objectives — masked nucleotide modeling, RNA secondary structure prediction, and RNA annotation ...
Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...
A scientific revolution is underway as researchers push to bring atomic-level precision, once reserved for small molecule ...
RNA Timeline: A History in Hybridization and Structure Alexander Rich and David Davies discover the double-stranded RNA helix and show that polyribo U and polyribo A hybridize spontaneously.6 Ben Hall ...
In contrast to conventional protein-targeting and DNA-based medicines, RNA can theoretically target any gene of interest ... Another key benefit of RNA-based drugs is the speed at which they can be ...