Like haemoglobin, it combines reversibly ... which for the first time reveals the general nature of the tertiary structure of a protein molecule. Before such a programme is embarked upon, however ...

Rhinesmith, S. H., Schroeder, W. A., and Pauling, L., J. Amer. Chem. Soc., 79, 4682 (1957).

For the first time, he could see what a molecule of haemoglobin looked like in 3D. Using lectures and programmes from the BBC archive, Josephine McDermott tells the story of how his fellow ...

We hear about the moment Dr Max Perutz discovered the haemoglobin structure. Our expert is Professor Sir Alan Fersht, who is a chemist at the Medical Research Council Laboratory of Molecular Biology ...

The top pathways were selected based on p-value<0.05. Based on the docking results for each protein and drug molecule, the drug–protein complex with the lowest binding energy was used as the initial ...

so having the cryo-EM structure was very helpful," Yeo said. "It was stunning to see the direct overlay of the small molecule and these cancer mutations, which we could not have imagined without ...

We report the unusual case of a patient found to have a low glycosylated haemoglobin (HbA1c) despite having recently been diagnosed with diabetes mellitus type 2. The patient, who was not anaemic, ...

Biology+ Joint Research Center, School of Chemical Engineering and Technology, Zhengzhou University, Zhengzhou 450001, China ...