A study reveals cannabis use may exacerbate synaptic deficits in young adults at risk for psychosis, particularly during critical brain development periods.

Synaptic plasticity is the basis of information storage in the brain. Two of the most studied forms of plasticity, long-term potentiation (LTP) and long-term depression (LTD), involve both ...

Analysis of tissues also showed increased neuronal synaptic density and decreased formation of phosphorylated-tau aggregates and amyloid-β plaques. The mice tolerated diAcCA well.

Recent studies indicate that loss of CD2AP in neurons leads to reduced spine density and impaired synaptic plasticity, key mechanisms underlying memory loss in AD .