▎药明康德内容团队编辑（来源：北京大学）神经传递是大脑信息交流的基础，其过程主要依赖于两种类型的囊泡：含有神经肽的大致密核心囊泡（Large dense core vesicle，LDCV）和含有小分子神经递质的突触小囊泡（Synaptic ...

在一项新的研究中，德国马克斯-德布吕克分子医学中心原位结构生物学实验室组长Misha Kudryashev教授及其同事们揭示了突触小泡（synaptic vesicle ...

Synaptic vesicle docking and fusion are mediated by the assembly of a stable SNARE core complex of proteins, which include the synaptic vesicle membrane protein VAMP/synaptobrevin and the ...

Using cryo-electron tomography, the team was able to visualize synaptic vesicles (SVs) in 3D and confirm a potentially important protein-protein interaction. They also broadened our understanding ...

近期， 中国科学院 生物与化学交叉研究中心刘聪课题组和美国辛辛那提大学医学院刁佳杰课题组在 eLife 上合作发表了一篇题为 “N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine” 的研究论文 ...

To do this, the synaptic vesicle must dock at the membrane of the presynaptic neuron and dump its content into the synapse, where it moves to particular receptors on the postsynaptic neuron.

Developing a FRET sensor for synaptic vesicle zinc. Currently Funded by the CU Signaling and Cellular Regulation Training Program. I love working with neurons and understanding their basic mechanisms.

(3) This causes synaptic vesicles to fuse with the terminal membrane, releasing neurotransmitter into the gap between neurons, known as the synaptic cleft. (4) The neurotransmitters bind to ...

This was due to the pausing of the synaptic vesicles responsible for transmitting neural signals in their cells. Once the ...