These include the expression of molecules called cytokines and co-stimulatory molecules, which are essential for stimulating T cells and generating effective T-cell responses. The authors show ...

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and ...

Citation: Successful CAR-T cell therapy for end-stage multiple myeloma using advanced cellular product performed in Hong Kong (2025, March 27) retrieved 27 March 2025 from https://medicalxpress ...

Our immune systems develop to recognize what is foreign within our bodies. As immune cells are generated in the bone marrow ...

New research from the University of Chicago shows how a specially trained population of immune cells keeps the peace by ...

Final phase 2a results showed that CAN-2409 led to a median overall survival of 24.5 months in immune checkpoint ...

Here, we evaluate gastric and gastro-oesophageal junction (G/GEJ) adenocarcinomas for their expression of programmed death-ligand 1 (PD-L1), infiltration by CD8+ T cells and the relationship of both ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

Researchers found that accelerating the brain's waste removal system could have tremendous implications for our memory.

Candel Therapeutics has identified a subpopulation of lung cancer patients living longest on its oncolytic virus, leading the biotech to narrow its focus as it heads towards a potentially ...

Candel Therapeutics (CADL) announced final survival data from a phase 2a clinical trial of CAN-2409 in patients with stage III/IV NSCLC, ...