Indeed, recent evidence showing that double-stranded DNA stimulates innate immune cells to produce type I interferons (IFNs) in a TBK1- and IRF3 (interferon-regulatory factor 3)-dependent manner ...
View Full Profile. Learn about our Editorial Policies. When STING is triggered, TANK-binding kinase (TBK1) activates and leads to interferon production. However, Tan and his team wanted to identify ...