Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Toll-like receptor 4 (TLR4) signaling at the ...

Washington University School of Medicine in St. Louis, St. Louis, MO.

The Center for Cell Signaling in Gastroenterology serves as a hub that provides access to state-of-the-art research resources and expertise on digestive diseases to multidisciplinary groups of basic ...

However, the impact of DuoHexaBody-CD37 on direct cytotoxic signaling has not yet been studied. Here we demonstrate that DuoHexaBody-CD37 induces direct cytotoxicity in DLBCL-derived tumor cell lines ...

1Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia.

and conducted experiments demonstrating that the protein is necessary for the CD8 + T cell signaling pathway. To do so, the scientists extracted T cells from mice genetically engineered to lack ...

At its third attempt, Mesoblast has secured FDA approval for Ryoncil as a treatment for children with graft-versus-host disease, the first-ever approval for a mesenchymal stromal cell (MSC ...