This is an important study that advances our understanding of centriole biogenesis and structure and is supported by convincing evidence based on knockout cell lines, immunoprecipitation, and ...

Concrete, steel and wood are some of the most common choices to compose the structure of stairs due to their high strength and versatility. But, when combined, these different materials expand ...

For example, Asian elephants, a species with a notably low cancer prevalence, have over 20 copies of a tumor suppressor gene (TP53) compared to our own lone copy. However, scientists are yet to ...

Plants are very important living things. They have lots of jobs, such as providing animals with food and releasing oxygen into the air. To survive and carry out these jobs, they all need three ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States ...

From a molecular viewpoint, uLMS contains complex karyotypes, with numerous chromosomal aberrations and frequent deletions affecting chromosomal arms 2p, 2q, 10q, and 13q, as well as amplifications on ...

Comprehensive genomic studies of ACC have revealed recurrent mutations in critical pathways, including Wnt/β-catenin (ZNRF3, CTNNB1), p53-driven apoptosis and cell cycle regulation (CDKN2A, CDK4, RB1, ...