When exposed to glutamate, the organoids—particularly the ones derived from patients with neurodegenerative ...

The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic buildup of the notorious tau protein, which can contribute to Alzheimer ...

Tau is a protein that has received national mainstream recognition for its potential negative impact to the brain. This review succinctly provides information on the structure of tau and its normal ...

The scans are also expensive and not available at all hospitals. More sensitive ways to detect amyloid and tau, another protein related to the disease, are possible by analyzing spinal fluid ...

A major characteristic of Alzheimer’s is the accumulation of a protein called tau within brain cells. This buildup is thought to disrupt normal cell function and contribute to the widespread brain ...

Stem cell scientists from the University of Southern California (USC) and elsewhere have found a way to potentially clear out the buildup of tau protein in the brain, which is associated with the ...

Although advances have been made in the development of techniques to detect biomarkers of early Alzheimer's disease, such as amyloid- β and tau proteins, these indicators do not fully explain the ...

A research team at the University of Cologne discovered that the 1N4R tau protein isoform plays a key role in Alzheimer’s disease by mediating the toxic effects of protein clumps in brain cells. Using ...

USC Stem Cell scientists discover a new way to rid cells of toxic tau protein in a study involving mice and lab-grown human “mini-brains,” known as organoids. The neurotransmitter glutamate is ...