Compared to Danishefsky’s diene, Rawal’s diene suffers from low commercial availability, limited scalability, and obscure stability issues, which strictly limits its usability. Herein, we present an ...

At the Joint ENC-ISMAR Conference 2025, Bruker Corporation, the leading provider of Nuclear Magnetic Resonance (NMR) spectroscopy solutions, announced the successful development and testing of the ...

Early Bird Fees are as follows: RSC Member (early bird) = £160 RSC Non-Member (early bird) = £170 RSC Member Student (early bird) = £140 RSC Non-Member Student (early bird) = £150 There is an open ...

College of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk 38541, South Korea College of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, Gimhae, Gyeongnam ...

The celite was washed with 2 mL of THF (3 times) and the clear solution was concentrated to 5 mL. By slow evaporation a microcrystalline solid was obtained. Yield 71%. M. p. 161–163°C. 1 H-NMR (CD 3 ...

The endoplasmic reticulum (ER) is responsible for folding secretory and membrane proteins, but disturbed ER proteostasis may lead to protein aggregation and subsequent cellular and clinical ...

We dissolved MLN4924 (1 mM, in DMSO) (Selleckchem., Houston, TX, USA) to medium or egg water and yielded a final MLN4924 concentration of 1 μM. Controls were treated equivalent volumes of DMSO. EPC ...

Cyclic peptide natural products have evolved to exploit diverse protein targets, many of which control essential cellular processes. Inspired by a series of cyclic peptides with partially elucidated ...