Pancreatic ductal adenocarcinoma (PDAC) is notorious for a dense fibrotic stroma that is interlaced with a collagen-based extracellular matrix (ECM) that plays an important role in tumor biology.

In brief, TAMs induce epithelial-mesenchymal transition (EMT) in tumor cells, giving them a migratory phenotype. They promote extracellular matrix (ECM) remodeling, allowing tumor cells to migrate ...

Initiation of Phase 1/2 combination trial with PYX-201, an extracellular ADC targeting Extradomain-B Fibronectin (EDB+FN) and ...

Pyxis Oncology (PYXS) announced significant progress in its clinical program for PYX-201, a first-in-concept antibody-drug conjugate, ADC, that ...

Jan. 28, 2025 — A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study suggests that doctors may need to ...

Although common, the cause of these hernias is unknown, and the only treatment ... Cancer Vaccine Shows Promise for Patients With Stage III and IV Kidney Cancer Feb. 5, 2025 — Researchers report ...

Police said some thieves are plugging a high-tech device into a vehicle’s on-board diagnostics (ODB) port, to be able to ...

鳞状细胞癌与基底细胞癌均来自于角质形成细胞的癌变，黑色素瘤来源于黑色素细胞癌变，因此在第一部分内容分析BCC，SCC,黑色素瘤细胞生态图谱后，研究团队将目光聚焦于角质形成细胞以及黑色素细胞。健康角质形成细胞和肿瘤角质形成细胞的二级聚类导致明显分离的健 ...

February 6, 2025 (La Mesa) – Aiming to help patients be “discharged with dignity,” Sharp Grossmont Hospital held a clothing ...

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