Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

Police said some thieves are plugging a high-tech device into a vehicle’s on-board diagnostics (ODB) port, to be able to ...

However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...

Pyxis Oncology (PYXS) announced significant progress in its clinical program for PYX-201, a first-in-concept antibody-drug conjugate, ADC, that ...

Initiation of Phase 1/2 combination trial with PYX-201, an extracellular ADC targeting Extradomain-B Fibronectin (EDB+FN) and ...

D tumoroid models transform cancer research, accurately reflecting tumor biology and enabling effective drug testing and ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

The Under-oil Open Microfluidic System enhances tumor cell-ECM interaction studies, improving anti-metastatic drug testing for triple-negative breast cancer.

(Bottom middle) Physical barriers: dense ECM and CAFs in the CRC tumor stroma create physical barriers that impede CAR-T cell infiltration and cytotoxic function within the tumor. (Bottom right) ...

A brain tumor is a mass of abnormal cells that grow in the brain. Brain tumors can be benign (non-cancerous) or malignant (cancerous) and can start anywhere in the brain. Malignant tumors grow rapidly ...

The hope is that these devices could make it possible to cure complex brain tumours, eliminate cancers that have metastasised to distant organs, and generally limit the toll which cancer treatment ...