It examines how the mechanical stiffness of the extracellular matrix (ECM), a network of proteins that surrounds cells and tissues in the body, impacts tumor development. "Tumors evolve through a ...

The researchers found that the treatment that included sulfuretin and two synthetic compounds altered the function of a ...

A collaborative research team from The University of Hong Kong (HKU) and West China Hospital of Sichuan University has made a ...

The researchers designed an efficient approach for fabricating engineered Pts-based nano-aircraft carriers with graded drug ...

Non-cancer cells exist alongside the cancerous ones in the extracellular matrix (ECM), which is a network of different molecules in all tissues and organs that provide structure for the cells. The ECM ...

Understanding the molecular cross-talk that occurs within the microenvironment between tumor cells and the ECM/other stromal cells may point to opportunities for cotargeting of the tumor and ...

Professor Yuxiong Su, Professor Gao Zhang and Professor Jingya Pu. A collaborative research team from The University of Hong ...

"Our work focused on fundamental understanding of ultrasound-mediated cancer cell killing and the effect of the ECM binding spacing on it," explains S Manasa Veena, Ph.D. student in BE and first ...

Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy ...

Adhesive Interactions Influencing Metastases Integrins are the major extracellular matrix (ECM) receptors, and integrin-mediated adhesive interactions between tumor cells and the components of ...