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Parabilis Medicines (formerly Fog Pharmaceuticals), a clinical-stage biopharmaceutical company committed to creating extraordinary medicines for people living with cancer, is presenting preclinical ...
Center for BioAnalytical Chemistry, Hefei National Laboratory of Physical Science at Microscale, University of Science and Technology of China, Hefei 230026, China Center for BioAnalytical Chemistry, ...
Figure 1: Representative images of the induction of autophagy and the outcome of its suppression. Figure 2: The role of autophagy in development and differentiation in mammals.
Explore the impact of 3D models in drug discovery and how they enhance predictive insights in pre-clinical research.
Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.