其激活过程如下：Wnt 蛋白与细胞膜上的 Frizzled（FZD）受体结合，激活低密度脂蛋白受体相关蛋白 5 和 6（LRP5/6）共受体；这一过程触发 Dishevelled（DVL）介导的 β-catenin 破坏复合物（DC）解离，DC 由 AXIN、APC、GSK - 3β 和 CK - 1α 组成，DC 解离后失去降解 β-catenin 的 ...

The authors find that the expression of notum, a Wnt inhibitor that is triggered after any cut ... Further analysis should be shown: i) Demonstration that the intensity of the band increases after APC ...

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