A recent study has unveiled the critical roles of two transcription factors, MAFB and CEBPA, in the development of ...

1Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng, China.

A recent study has uncovered the pivotal role of the transcription factor SOX9 in the development of hypospadias, a common ...

On the occasion of the 30th anniversary of the discovery of the first mammalian Wnt-gene, this Focus issue features a personal perspective from Roel Nusse and Harold Varmus on past, current and future ...

CHD is generally understood to derive from dysfunction in the growth, morphogenesis, and/or differentiation of cardiac-fated progenitor cell derivatives; however, the genetic and molecular networks ...

Hypospadias is characterized by an ectopic urethral opening and abnormal penile curvature, affecting approximately 1 in 200 live male births.

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related mortality worldwide. Current treatment modalities are few or ...

A recent study has uncovered the pivotal role of the transcription factor SOX9 in the development of hypospadias, a common congenital condition that ...

Introduction: Lung adenocarcinoma (LUAD) therapies are plagued by insufficient immune infiltration and suboptimal immune responses in patients, which are closely associated with the hyperactive ...

Thus, understanding the molecular mechanisms driving HCC is essential for developing new therapeutic strategies. A growing body of research highlights the crucial role of the Wnt signaling pathway ...