ST316, a β-catenin/BCL9 antagonist, demonstrated safety, target engagement, and early antitumor activity in advanced solid ...

A recent study has unveiled the critical roles of two transcription factors, MAFB and CEBPA, in the development of ...

Hypospadias is characterized by an ectopic urethral opening and abnormal penile curvature, affecting approximately 1 in 200 live male births.

研究人员探究反复着床失败（RIF）病因，发现 Wnt/β -catenin 和 PI3K-AKT-mTOR 通路异常，为 RIF 治疗提供新思路。 ### 反复着床失败：生育难题背后的分子秘密 在生育的奇妙旅程中，反复着床失败（Recurrent implantation failure，RIF）成为了许多夫妻难以跨越的障碍。

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related mortality worldwide. Current treatment modalities are few or ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

Particularly noteworthy among these compounds are 6-gingerol and 6-shogaol, which have been recognized for their potent ...

本研究聚焦卵巢癌进展的关键因素PNO1，探讨其通过AKT/Wnt/β-catenin通路影响肿瘤细胞生长、侵袭和干性，为卵巢癌治疗提供新靶 ...

Therapeutics announced the presentation of new clinical data from its ongoing Phase 2 trial with stenoparib monotherapy in ...