Patients: Patients with active IBD (n=42), disease specificity controls (n=8), and normal controls (n=12) were investigated. Methods: Expression and activation of STAT1 were assessed by western ...

这篇综述探讨了 ZEB1 和 ZEB2 在肿瘤进展中的复杂作用，其影响因组织和癌症类型而异。 引言 上皮 - 间质转化（EMT）是一个可逆的生物学过程，上皮细胞在这个过程中失去细胞极性和细胞间黏附，获得间质表型。在胚胎发育、伤口愈合和组织稳态中，EMT 发挥着 ...

Janus kinase/signal transduction and transcription activation (JAK/STAT) pathways were originally thought to be intracellular signaling pathways that mediate cytokine signals in mammals. Existing ...

Methods The SPR was activated in murine and primary human alveolar macrophages prior to analysis of signal transducer and activator of transcription factor 1 (STAT1) activation, iNOS mRNA and protein ...

After four days, Mobile World Congress has come to an end. During our time in Barcelona, we saw countless phones, wearables, AI implementations and gadgets on display.

Respiratory viral infections are a major global public health concern, and current antiviral therapies still have limitations. In recent years, research has revealed significant similarities between ...

Combined, these findings show that CMA displays a broad targetability on multiple steps of the EMT process and indicate a substantial role of CMA in regulating the stability of pro-metastatic and ...

Objectives In this study, we employ a multiomic approach to identify major cell types and subsets, and their transcriptomic profiles within the infrapatellar fat pad (IFP), and to determine ...

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