The acetate uptake pathway in Y. lipolytica could function as an acetyl-CoA shortcut, which has been demonstrated to achieve metabolic optimality in producing polyketides (Liu et al., 2019b).

In addition, it increases acetyl coenzyme A (acetyl-CoA) synthesis for histone acetylation, which is a key epigenetic regulator of the expression of several M2 marker genes. M2 macrophages maintain ...

Some of those acetyl groups are turned back into acetyl-CoA and consumed for energy, while others are recycled to activate a different set of genes. Clearly there’s a lot of metabolic activity ...

Carling D, Clarke PR, Zammit VA, Hardie DG. Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA ...

The subjects were six obese females (nineteen to fifty-six years old). The medical histories revealed that they had tried a number of diets and drugs, and before admission they had all maintained ...

Both Samuel and David, as youths, fulfill God's will; David and Goliath (1 Sam. 17:26,34-37,47); David gains the heart of all (18:16); Saul's jealousy of David (18:9-11). And David said to Saul, Let ...

State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China Department of Pharmacology and Chemical ...

Department of Environmental Science, Zhejiang University, Hangzhou, Zhejiang 310058, China National Demonstration Center for Experimental Environment and Resources Education, College of Environmental ...