北京大学肿瘤医院内蒙古医院微创介入科等研究机构的研究人员针对这一问题，开展了以 “靶向 NETO2 抑制肝癌细胞增殖、侵袭和迁移并失活 STAT3/C-MYC 通路” 为主题的研究。研究发现，NETO2 敲低能够抑制 HCC 细胞的增殖、侵袭和迁移，同时使 STAT3/C-MYC 通路失活。这一研究结果意义重大，为肝癌的治疗提供了新的潜在靶点，有望改善 HCC ...

Background and aims c-Myc is highly expressed in pancreatic multipotent progenitor cells (MPC) and in pancreatic cancer. The transition from MPC to unipotent acinar progenitors is associated with ...

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery ...

Q4 2024 Earnings Call Transcript March 20, 2025 Monte Rosa Therapeutics, Inc. beats earnings expectations. Reported EPS is $0 ...

This pathway regulates essential processes such ... In the nucleus, β-catenin activates downstream genes like c-Myc and Cyclin D1, promoting cell proliferation and survival.

Figure 5 Cancer pathway of indispensable genes. (A–C) are the pathways that EGFR, MAX, MNT, SMAD3 associated with MYCN or MYC, respectively. Finally, we analyzed the indispensable node that are ...

He also touched on several issues including education investment, workforce development and career pathways, addiction and mental health challenges, children's services and foster care ...