Previously, the opioid analgesic drug JCT801 was reported to induce cell death via disruption of pH homeostasis in pancreatic cancer cells. Here, the authors investigate the metabolic mechanisms ...

To evaluate if an unfavorable maternal environment induced by hyperglycemia, hypoxia, and oxidative stress status impairs the morphological development of pancreatic islets in the fetuses on days 18 ...

糖尿病是一类由胰岛素分泌不足或胰岛素抵抗引起的代谢性疾病。通常分为1 型糖尿病（type 1 diabetes mellitus ，T1DM ）、T2DM 、妊娠糖尿病和其他原因导致的特定类型糖尿病。其中，T1DM 和T2DM是目前最常见的糖尿病类型。糖尿病发病机制复杂，包括胰岛β细胞功能 ...