Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan ...

Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for innovative therapeutic strategies.

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact ...

How alterations in cell metabolism translate into specific developmental gene programs remains a major question. This study ...

Scientists have the technology to grow humans in Petri dishes, but they say there are better uses for it: to combat aging.

University Grenoble Alpes, CEA, INSERM, UA13 BGE, CNRS, CEA, 38000 Grenoble, France ...

New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in ...

Mar. 26, 2025 — Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the ...