Learn how drug absorption and predictive modeling drive advancements in pharmaceuticals and precision medicine.

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Both of these reports lacked pH measurements and interpretation of drug structures and pH and pKa values in relation to ionization and nonionization and solubility, all of which are necessary to ...

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This suggests that Cdk5/DARPP-32 provides a feedback signal that compensates for an upregulated PKA pathway. The fact that ΔFosB accumulates following repeated cocaine exposure and persists ...

Harada et al. 3 have now identified PKA as the kinase that phosphorylates serine 112 of BAD. They did this by purifying the kinase activity, which was present principally in heavy membrane ...

The relative proportion of B(OH) 3 and B(OH) 4 – adsorption varies depending on the solution pH. At pH values < pKa (9.3), B(OH) 3 is the predominant solution form, while above this pH the predominant ...