Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.

This valuable study introduces a self-supervised machine learning method to classify C. elegans postures and behaviors directly from video data, offering an alternative to the skeleton-based ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

Most SSMs can be broken down into two key components: inputs and integrators ( Bogacz et al., 2006 ). Inputs encode the drift rate – the rate of evidence accumulation – and integrators encode the ...

For example, the tendency for behavioural responses in a range of cognitive domains to oscillate over time has been studied extensively. Recently, however, the phenomenon of behavioural oscillations ...

When navigating environments with changing rules, human brain circuits flexibly adapt how and where we retain information to help us achieve our immediate goals.

Aβ is believed to play a significant role in synaptic degeneration observed in Alzheimer’s disease and is primarily investigated as a secreted peptide. However, the contribution of intracellular Aβ or ...

The article presents important findings describing the role of IL27 in maintaining HSCs at steady state, and in emergency haematopoiesis in response to T. goodii by limiting the inflammatory monocyte ...