tsRNAs 作为基因表达关键调控因子，在癌症研究中意义重大，本文对此进行全面综述。 # 非编码 RNA 研究新进展：tRNA 衍生小 RNA（tsRNAs）在基因调控和癌症中的关键作用 在生命科学的微观世界里，非编码 RNA 的研究一直是热门领域，近年来更是取得了不少突破性 ...

HC Bioscience is shutting down after conducting preclinical models for a transfer RNA (tRNA) asset designed to treat ...

研究人员为探究 PYROXD1 保护 tRNA 连接酶复合物（tRNA-LC）机制，解析相关结构，明确其作用及意义。 在生命的微观世界里，RNA 分子如同忙碌的 “小工匠”，参与着各种重要的生命活动。其中，tRNA（转运核糖核酸）在蛋白质合成过程中起着关键的 “搬运工” 作用 ...

Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. tRNAs function at specific sites in the ribosome during translation ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive tract diseases, positioning these molecules as potential biomarkers for ...

The Technion researchers' study describes an evolutionary scenario where protection arises from a reduced level of tRNA (transfer RNA), a molecule critical for gene translation. "Studies on ...

US-based biotechnology company Alltrna is developing transfer RNA (tRNA)-based therapies that aim to offer a broad solution for thousands of rare genetic diseases by targeting common mutations ...

∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001. IARS2, isoleucyl-tRNA synthetase 2; PDAC, pancreatic ductal adenocarcinoma. Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of ...

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related mortality worldwide. Current treatment modalities are few or ...