SAN DIEGO, April 03, 2025 (GLOBE NEWSWIRE) -- aTyr Pharma, Inc. (Nasdaq: ATYR), a clinical stage biotechnology company ...

RNA therapeutics market is expanding, driven by advancements in gene therapy, personalized medicine, and RNA-based drug delivery, along with rising research in mRNA vaccines, antisense ...

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...

Werner held roles at Bristol Myers Squibb, AstraZeneca and Novartis before landing at Alltrna, where she works to develop tRNA-based treatments for a range of diseases.

为解决油棕因遗传和环境因素导致的生产力问题，海南大学等研究人员开展了油棕 tRNA 修饰及其在果实成熟过程中动态变化的研究。他们鉴定出 48 种 tRNA 修饰及 164 个相关基因，发现多数修饰在果实发育中减少，且 tRNA 修饰与脂质积累相关，为提高油棕产量提供新思路。

SAN DIEGO, March 27, 2025 (GLOBE NEWSWIRE) -- aTyr Pharma, Inc. (Nasdaq: ATYR) ("aTyr" or "the Company"), a clinical stage biotechnology company engaged in the discovery and development of first-in-cl ...

胶质母细胞瘤（GBM）是恶性程度最高的原发性中枢神经系统肿瘤，预后极差。尽管接受了手术、放疗和化疗，GBM患者的5年相对生存率仍为6.8%，是恶性脑肿瘤中最低的。血管生成拟态（VM）与GBM的不良预后密切相关。了解VM形成的机制和确定靶向治疗对于改善 ...

中国科学院分子细胞科学卓越创新中心（上海生化与细胞所）周小龙课题组研究RNA代谢与线粒体疾病。课题组主要以人蛋白质生物合成过程中关键分子，包括氨基酰-tRNA合成酶 ...

SAN DIEGO, March 27, 2025 (GLOBE NEWSWIRE) -- aTyr Pharma, Inc. (Nasdaq: ATYR) (“aTyr” or “the Company”), a clinical stage ...

RNA（核糖核酸）的修饰在RNA分子的功能、完整性、代谢和生物合成中起着至关重要的作用。目前已发现超过100种RNA修饰，其中大多数发生在转运RNA（tRNA）中，但它们也可以在核糖体RNA（rRNA）、小核RNA（snRNA）、信使RNA（mRNA）和长非编码RNA（ncRNA）中找到。

(A) Bar plot of IARS2 transcription level in different cancer types. (B) TCGA and GTEx databases showed IARS2 transcription level was higher in tumor tissue compared with normal pancreas tissue.

A Boston biotech try­ing to bring trans­fer RNA (tR­NA) bi­ol­o­gy to the drug de­vel­op­ment field has shut­tered op­er­a­tions, End­points News has learned.