This project will develop state of the art wearable sensors to measure antimicrobial resistance, which is key to prevent antibiotic misuse.

Structural Comparison of SHV-1 (PDB ID: 3N4I) and PDC-3 (PDB ID: 4HEF) β-Lactamases. Catalytic serine S 70 (SHV-1) and S 64 (PDC3) are highlighted using stick representation. Important loops ...

In particular, this should pertain to plasmid-encoded resistance genes encoding enzymes degrading antibiotics with an extra-cytoplasmic target (e.g. beta-lactamases). Extended spectrum beta-lactamases ...