Antibiotic resistance is a pressing issue within the realm of global health, posing significant challenges, particularly in ...

UCL School of Pharmacy, University College London, London WC1N 1AX, U.K. Research Service, Department of Veterans Affairs Medical Center, Louis Stokes Cleveland, Cleveland, Ohio 44106, United States ...

由于肺炎克雷伯菌的致病性，人们通常会使用抗生素，特别是 β- 内酰胺类抗生素进行治疗。然而，这个 “杀手” 却在不断进化，它获得了各种可移动遗传元件，比如质粒，这些元件能让它表达耐药基因和毒力因子，产生 β- 内酰胺酶（包括碳青霉烯酶），破坏 ...

Prophages are bacteriophages that integrate their genomes into the bacterial chromosome. This research aimed to analyze and characterize prophages integrated into 44 Pseudomonas aeruginosa strains ...

Bacteria are clever. Strep and some other bacteria combat antibiotics by secreting beta-lactamases that inactivate piperacillin. We found the approach is totally irrelevant in the context of Lyme ...

State Key Laboratory of Bioreactor Engineering, Shanghai Collaborative Innovation Centre for Biomanufacturing, East China University of Science and Technology, Shanghai 200237, P. R. China ...

"Bacteria are clever," Jutras said. "Strep and some other bacteria combat antibiotics by secreting beta-lactamases that inactivate piperacillin. We found the approach is totally irrelevant in the ...

Using third-generation cephalosporins has become compromised by the increasing variety of beta-lactamases within Gram-negative bacilli. Avibactam is a potent inhibitor of many beta-lactamases, which ...