The discoveries in this research pertain to diseases that accumulate 4R tau. Merging advanced techniques such as transmission electron microscopy and molecular dynamics simulations with in-vitro ...

Alzheimer’s disease, a devastating neurodegenerative disorder, is closely linked to the accumulation of tau protein in the ...

both neuronal and glial tau accumulation demonstrate 4R-tau in the cerebral cortices. Brain extracts from patients with PSP show a distinctive pattern of tau fragments consisting of a predominant ...