GeneVentiv Therapeutics, a gene therapy company, today announced it has signed a global licensing agreement with Duke ...

Discover how an emerging technology called tRNA therapy could become the next big thing in genetic disease treatment.

Cell And Gene Therapy Market Size and ForecastThe global cell and gene therapy market is projected to witness significant ...

We hypothesized that the AAV capsid, which has naturally evolved to overcome many of these barriers, could be repurposed as a protein delivery vehicle. Supporting this hypothesis, our previous domain ...

直到3月20日这项登上《Nature Biotechnology》的研究“Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic ...

然而，AAV载体的包装容量限制了其在递送大基因载荷方面的应用。例如，一些用于基因编辑的工具，如CRISPR–Cas9系统，其基因序列长度超出了AAV载体的包装范围。此外，为了实现细胞类型特异性表达，通常需要在AAV载体中加入增强子等调控元件，这进一步压缩了 ...

Discussion: The lack of pathology, combined with the robust mucosal and systemic immune responses, suggests that pulmonary delivery of adjuvanted RSV-VLPs may provide effective protection without the ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Read more about reducing risks from gene therapy Mateusz Durbacz, MSc, UT Southwestern Medical Center, Dallas warned that “while genome editing using AAV offers significant advantages, it also ...