对CD16a作用机制的深入理解,促使我们开发出多种通过研究单克隆抗体(mAb)或自然杀伤细胞(NK细胞)来增强抗体依赖的细胞介导的细胞毒性(ADCC ...
Reduction in ADCC activity has the potential for a more ... receipt of early proof of concept results from STAR-0310 Phase 1a trial; the aims and objectives of the STAR-0310 Phase 1a trial ...
and associated with enhanced or silenced effector functions (ADCC or complement-dependent cytotoxicity) are being investigated in clinical trials. Among the challenges to be faced in the next 10 ...
In the trial for rheumatoid arthritis — which involved ... and it is presumed to work more effectively by complement lysis rather than ADCC. It has also been shown to have a tighter binding ...
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