研究人员针对 ATM 突变前列腺癌开展研究，发现 ATR 和 DNA-PKcs 双重抑制有疗效，Compound B 或可用于联合放疗。 在晚期去势抵抗性前列腺癌（CRPC）中，DNA 损伤反应（DDR）基因共济失调毛细血管扩张突变（ATM）发生突变的情况较为常见。尽管聚（ADP - 核糖）聚合酶 ...

The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.

CCTV shows the moment Tommy Mitchell used a Land Rover Defender in an attempt to steal an ATM - a swab of the vehicle’s steering wheel later linked him to the crime. Did you know with a Digital ...