TMC207 inhibits the proton pump of mycobacterial ATP synthase, a critical enzyme in the synthesis of ATP for Mycobacterium tuberculosis. Resistance is achieved through mutations at position 63 or ...

研究结论表明，线粒体蛋白水平可能与先天性心脏、泌尿、神经系统、耳部和肢体畸形存在因果关系。这一发现突出了线粒体功能障碍在结构性出生缺陷发病机制中潜在的病因学作用。丙酮酸脱氢酶激酶同工酶 1 和 ATP 合酶 β 亚基线粒体水平降低与先天性心脏病风险降低相关，说明丙酮酸代谢和 ATP 生成过程的紊乱可能干扰心脏发育过程，导致心脏结构缺陷。39S 核糖体蛋白 L14 ...

基于结构的数字化药物研发 ：水木药业基于自有冷冻电镜集群、GPCR平台和AI技术,全球第一个成功获取了新一代肥胖靶点GPR75的高分辨冷冻电镜结构,大幅提升了小分子药物发现和优化效率,有机会成为超越斯美格鲁肽的新一代减肥小分子药物。

These tournaments attract the best players in the world and are considered the most prestigious events in tennis. In addition to the Grand Slam tournaments, the ATP Tour and WTA Tour organize ...

TSN's five national feeds deliver more than 1,600 hours of world-class tennis a year, including the ATP 250 Series, World Tour 1000 and 500 series events. Get even more digital-only court feeds ...

Boostaro is manufactured by a reputable company dedicated to creating high-quality dietary supplements focused on men's ...

Antitachycardia pacing (ATP) refers to the use of pacing stimulation techniques for termination of tachyarrhythmias. Such techniques can be automatically applied using implantable cardioverter ...

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