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生物通
26 天
新型羧酰胺衍生物:改善大鼠高血脂的潜在 “基因调控密码”
为探究新型羧酰胺衍生物对高血脂的分子作用,研究人员以 Triton WR-1339 诱导的雄性高血脂大鼠为模型,对比非诺贝特(fenofibrate)开展研究。结果显示,3 种新型化合物可改善高甘油三酯血症,调节脂质代谢关键酶基因表达,意义重大。
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