胆管癌（CCA）预后差，缺乏有效治疗手段。研究人员开展了异鼠李素（Iso）对 CCA 作用的研究。结果发现 Iso 可通过 PI3K/AKT 通路抑制 CCA 细胞增殖、侵袭和转移，AKT1 可能是其治疗 CCA 的靶点，为 CCA 治疗提供新方向。

Microvascular proliferation was present both within the ... Figure 3: Mouse glioblastomas express Gfap, nestin, virally transduced Akt and Ras. Our data imply a central role for Ras and Akt ...

PI3K/Akt/mTOR, Wnt/β-catenin, NF-κB, Notch, and DDR pathways. These pathways are critical in regulating essential cellular processes such as proliferation, survival, differentiation, and metastasis.

New research has revealed that Schistosoma haematobium (S. haematobium), a parasitic infection affecting millions globally, ...

A breakthrough breast cancer pill, will now be offered on the NHS to thousands of women with advanced breast cancer. This is ...